Although appendicitis and IBS are entirely different conditions, their symptoms can overlap, as both can cause abdominal pain. So, what are the distinctive symptoms that can help differentiate between the two?

Key Differences: Appendicitis vs. IBS Symptoms

Both appendicitis and IBS cause abdominal pain, but they can be distinguished as follows: (1)(2)

Distinctive Symptoms of Appendicitis

Common signs that differentiate appendicitis include: (3)

• Pain worsens when pressure is applied to the painful area and then released.
• Feeling pain in the lower right abdomen when pressing on the left side.
• Bending the right leg towards the abdomen can ease the pain, while straightening the body worsens it.

Accompanying Symptoms:

• Loss of appetite.
• Nausea and vomiting (usually after the pain starts).
• Low-grade fever.

Distinctive Symptoms of IBS

Symptoms of IBS vary between individuals but typically include: (4)

• Bloating and gas: A hallmark symptom experienced in all cases.
• Changes in bowel habits: Such as recurring diarrhea, constipation, or alternating between the two.
• Changes in stool consistency: Including the presence of mucus or changes in stool firmness.
• Incomplete evacuation: A sensation of not fully emptying the bowels after defecation.

Diagnosis: Appendicitis vs. IBS

Differentiating between the two is critical, as appendicitis is a potentially life-threatening condition that often requires surgical removal, while IBS poses no significant health risks.

Doctors distinguish between the two based on: (3)(4)

1. Symptoms and Physical Examination

• Appendicitis: Pain localized to the lower right abdomen, with tenderness that worsens when pressure is released.
• IBS: No clear physical findings during an abdominal exam.

2. Blood Tests

• Appendicitis: Elevated white blood cell count (WBC) or C-reactive protein (CRP) indicating inflammation or infection.
• IBS: Typically normal blood tests, as IBS is a functional disorder rather than an inflammatory one.

3. Imaging Tests

• Appendicitis: Ultrasound or CT scan usually shows an inflamed appendix.
• IBS: Imaging studies of the digestive system are typically normal.

Symptoms alone can’t distinguish appendicitis from IBS, but they help guide the necessary tests. Ultrasound or CT scans are essential to confirm an appendicitis diagnosis. Visit our Emergency Department or consult with our Gastroenterologists to get the answers you need.

References

1. NIH - Symptoms & Causes of Appendicitis
2. NIH - Symptoms & Causes of Irritable Bowel Syndrome
3. MSD manuals - Appendicitis
4. Mayo Clinic - Irritable bowel syndrome